Alicia M. Pickrell, PhD
Virginia Tech School of Neurosciences
She / Her / Hers
This seminar will describe how the loss of Parkin-mediated mitophagy impacts human health and disease. The first part of the seminar will summarize her research on how defective clearance of damaged mitochondria (mitophagy) contributes to the selective death of dopaminergic neurons while the second part of the seminar will report new findings on how proper cell cycle control is also impacted by mitophagy.
About the Speaker: Dr. Pickrell received her PhD from University of Miami: Miller School of Medicine in 2012. As a graduate student with Dr. Carlos T. Moraes, her work identified neuronal subtypes particularly sensitive to mitochondrial defects and elucidated mechanisms by which mitochondrial DNA damage signaling contributes to stem cell senescence. From 2012-2017, she worked as a postdoctoral fellow with Richard J. Youle at the NIH where she shifted her focus on mitophagy. She started her own laboratory in 2017 at Virginia Tech to continue work in mitochondrial biology.
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