February 22, 2024: New Approach Methodology for Developmental Neurotoxicity: Past, Present and Future

Timothy Shafer, PhD

Principal Investigator

Center for Computational Toxicology and Exposure

US Environmental Protection Agency


Description: This presentation will review the need for alternative approaches for DNT testing and provide a brief historical perspective of research to meet this need. The current state of the field will also be presented with examples of how this area of research is currently impacting decision-making regarding pesticides and PFAS compounds. The presentation will then turn towards the future and discuss ongoing research as well as topics that might prove fruitful in the future.

About the speaker: Dr. Tim Shafer is a Research Toxicologist and Principal Investigator in the Biomolecular and Computational Toxicology Division in the Center for Computational Toxicology and Exposure in the Office of Research and Development at the U.S. Environmental Protection Agency. Tim earned his PhD from the Department of Pharmacology and Toxicology at Michigan State University.

For the past 15 years, Tim’s work has been directed towards development of new alternative methods for assessment of neurotoxicity and developmental neurotoxicity hazards of chemicals. He has published over 100 peer-reviewed journal articles, book chapters and reports; has received 8 Scientific and Technological Achievements Awards and Bronze and Gold medals for outstanding service to the Agency.

Dr Shafer has also served ORD as an Acting Branch Chief, Acting Assistant Laboratory Director for Human Health Research, Acting Director of the Integrated Systems Toxicology Division. In addition, he has held appointments and elected offices outside of EPA including serving on grant review panels (ALTOX3/NAL study section at NIH), Society of Toxicology Program Committee and Secretary/Treasurer of the Society of Toxicology’s Neurotoxicology Specialty Section, President of the International Neurotoxicology Association, and appointments as Associate Editor for the journal NeuroToxicology and to the Editorial Board of Toxicology and Applied Pharmacology.

Thursday, February 22, 2024, 12:00-1:15pm Eastern

Field Auditorium, Room 1112, Grainger Hall (9 Circuit Drive, Durham, NC)

This seminar will also be presented live via Panopto. Click HERE to join the livestream.

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