November 3, 2023: Macrophage-derived mechanisms of resolution of environmental lung injury

Marissa Guttenberg, PhD Candidate

Duke University Nicholas School of the Environment

Program: Integrated Toxicology & Environmental Health


Tighe Lab

Description: Acute ozone (O3) exposure causes lung inflammation via effects on alveolar macrophage (AMØ) function. Published data has described the integral role of AMØs in homeostasis, inflammation, and resolution responses following acute O3 exposure; however, there is a gap in the understanding of function dictated by ontogeny. This work aims to further understand both the specific AMØ populations involved in resolution of environmental lung injury as well as the mechanisms driving these responses.

About the speaker: Marissa is a 6th year PhD student in the Integrated Toxicology and Environmental Health Program at Duke University working in Dr. Robert Tighe’s lab. Her research focuses on the intersection between toxicology and human lung health, specifically air pollution effects. Marissa’s thesis centers around studying macrophage-derived mechanisms that promote resolution of ozone-induced lung injury. Marissa earned her B.S. in Nanoscale Science at the College of Nanoscale Science and Engineering as well as Minors in Business and Mathematics at SUNY University at Albany in 2018.

Wednesday, November 1, 2023, 11:30-12:45pm Eastern

Room A158, Levine Science Research Center, (308 Research Drive, Durham, NC)

This seminar will also be presented live via Zoom. Register* HERE for the livestream.

*Registration will not be available once the seminar begins.

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