Analytical Chemistry Core

What do we do?

The mission of the Analytical Chemistry Core (ACC) is to provide routine quantitative and qualitative analysis of organic contaminants on a routine basis to investigators in support of Duke SRC research projects. The ACC also develops novel methods for emerging contaminants of concern in environmental and biological samples on an as-needed basis. Finally, the ACC serves as a consulting and training resource for cutting-edge analytical chemistry needs within the Duke SRC.

Some examples of analytical services provided by the ACC include:

  • Quantitation of thyroid hormones in biological tissues
  • Analysis and characterization of current and emerging halogenated flame retardants (e.g. PBDEs and replacements) in environmental and biological samples
  • Quantitation of chlorpyrifos and its degradation products in natural and engineered systems
  • Broad-range analysis of polycyclic aromatic hydrocarbons (PAHs) in sediment and water
  • Identification and characterization of PAH transformation products in fish tissues

Analytical resources available to the ACC for these analyses include HPLC-MS/MS, high resolution HPLC-Orbitrap MS/MS, GC-MS, GC-ECD, and HPLC-UV-FLD systems.

As part of our ongoing efforts to understand human exposure to flame retardant chemicals, our laboratory is now offering free testing of foam from household furniture.  Our testing will determine whether or not 7 common flame retardant chemicals are present in furniture foam. This free testing is open to the public and each household can send up to 5 samples from furniture or other household products with polyurethane foam. For more information about why we’re doing this, what we’re doing, and how you can participate, visit the project’s website.


Who are we?

Dr. Lee Ferguson
Dr. Heather Stapleton
Dr. Ellen Cooper