Gregory J Cole, PhD
North Carolina Central University (NCCU)
Professor, Department of Biological & Biomedical Sciences
Dr. Cole’s longstanding research interest has been the role of the extracellular matrix in nervous system development, especially the function of the heparan sulfate proteoglycan agrin. These studies are currently focusing on elucidating the mechanisms by which agrin modulates the function of heparin-binding growth factors and morphogens, such as fibroblast growth factors (Fgfs) and sonic hedgehog (Shh), during zebrafish nervous system development. Studies in the Cole lab are employing genetic and molecular approaches to examine ocular, forebrain, and hindbrain development in response to ethanol exposure, and the subsequent changes in agrin, Fgf or Shh signaling. This research is funded by an NIH U54 Cooperative Agreement grant between UNC-Chapel Hill and NCCU.
Profile: https://legacy.nccu.edu/directory/details.cfm?id=gcole
Lab Website: https://sites.google.com/site/colelabpage/
