Jan 14, 2021: Persistent mitochondrial effects of early-life arsenic exposure in C. elegans

Headshot of Kathleen Hershberger, PhD

Kathleen Hershberger, PhD

Visiting Assistant Professor of Biology

Grinnell College

She / Her / Hers


Arsenic is a well-established environmental toxicant that contributes to the pathogenesis of a number of diseases including cardiomyopathy, neuropathy, and cancers. Carcinogenic effects may be regulated via epigenetic mechanisms, suggesting that effects of arsenic exposure may persist through multiple generations. Arsenic inhibits a number of enzymes in energy production that results in metabolic shifts that support disease pathogenesis, making mitochondria an important target of arsenic toxicity to further study. In this seminar, Dr. Hershberger will summarize her work using C. elegans to study the transgenerational and persistent effects of early-life arsenic exposure.

About the Speaker: Kathleen is currently a Visiting Assistant Professor of Biology at Grinnell College. Her research focuses on how genetic and environmental factors impact mitochondrial and whole animal health. Kathleen received her PhD in Pharmacology from Duke University in 2017 and then joined Dr. Joel Meyer’s lab in the Nicholas School of the Environment at Duke University as a Postdoc. In her free time, Kathleen enjoys spending time with her family, baking, reading, and exploring new places.

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