September 5, 2025: Leveraging high throughput screening data to learn new mitochondrial biology

Janine Santos, PhD

Staff Scientist, Mechanistic Toxicology Branch

NIEHS

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Description: The presentation will describe Tox21 data and how it was used to create genetic models that helped identify novel means of mitochondrial-driven intracellular communication.

About the speaker: Janine Santos received her Ph.D. in Genetics and Molecular Biology from the Federal University of Rio Grande do Sul in Porto Alegre, Brazil. During her Ph.D. studies. Dr. Santos worked on Genetic Toxicology using Drosophila melanogaster as a model system to understand the effects of dietary compounds under conditions of genotoxic stress. She then moved to NC for her post-doctoral fellowship at NIEHS to work on mitochondrial DNA metabolism. In 2006, Dr. Santos became faculty at the New Jersey Medical School and in 2013 returned to NIEHS. Her current line of research involves defining the impact of mitochondrial metabolism to the epigenome and transcriptome to better understand the effects of environmental agents that target this organelle.


Friday, September 5, 2025

Field Auditorium, Room 1112, Grainger Hall (9 Circuit Drive, Durham, NC)

This seminar will also be presented live via Panopto. Click HERE for the livestream.


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